The global mRNA therapeutics and mRNA vaccine market is witnessing steady growth, estimated to be worth USD 51.3 billion in 2023.

In recent years, mRNA vaccine and therapeutics market is propelled by the increasing demand for target-specific therapies to treat a wide range of diseases that cannot be treated with conventional drugs. mRNA refers to the messenger ribonucleic acid (single-stranded ribonucleic acid) that codes genes for protein expression. mRNA therapeutics and vaccines have recently gained the attention of pharmaceutical companies as a revolutionary drug class to treat infectious, chronic, and oncological disorders. Currently, mRNA vaccines have been used for the treatment of patients suffering from COVID-19 and other diseases such as genetic disorders, cancer, infectious diseases, and more.  Though mRNA Therapeutics and vaccines have shown significant potential in the treatment of diseases, the market has witnessed a steady decline due to strict regulatory guidelines and presence of pre-existing vaccines with other technologies in the market. Additionally, due to the transition of the current COVID-19 pandemic situation into an endemic by the end of this year, the mRNA therapeutics and mRNA vaccine market is anticipated to decline during the forecast period.

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Key Report Takeaway

• With over 195 candidates under development, mRNA therapeutics, and vaccines currently represent one of the fastest-growing drug classes in the pharmaceutical market.
• The pipeline features several drugs, which are being investigated across different phases of development; over 75% of the pipeline candidates are designed for delivery via the intramuscular and intravenous routes.
• Stakeholders are actively upgrading their existing capabilities to further enhance their respective product pipelines and comply with the evolving industry benchmarks.
• More than 345,000 patients have been recruited / enrolled in clinical trials registered for this novel class of therapies across different geographies.
• The growing interest is evident from the rise in partnership activity since 2021; clinical trial agreements have emerged as the most common type of partnership model adopted by drug developers.
• Several investors, having realized the opportunity within this upcoming segment, have invested over USD 11 billion across various funding rounds in the past nine years.
• Big pharma players have undertaken several initiatives, from proprietary product development to strategic investments, to tap the lucrative opportunity in this rapidly growing market.
• The market's evolution is likely to be driven by the rising need for novel drug candidates; we expect the future opportunity to be well-distributed across various routes of administration, therapeutic areas, and key regions.

Competitive Landscape of the mRNA Therapeutics and Vaccine Market

Currently, the mRNA therapeutics and vaccine market landscape features more than 35 companies engaged in evaluating over 195 mRNA therapeutics and mRNA vaccines across different clinical and development stages. In the coming years, several pharmaceutical companies such as Moderna, Merck, Sanofi, and Daiichi Sankyo will enroll in strategic partnerships with mRNA-based therapeutics and vaccine developers to expand their therapy development capabilities.

mRNA Therapeutics and Vaccine Market Geographical Outlook

The mRNA therapeutics and vaccine market based on geographical region is segmented into North America, Europe, Asia-Pacific, Latin America, the Middle East, North Africa, and the rest of the world. North America is dominating the mRNA therapeutic and vaccine market, holding the largest share of overall revenue. The National Institutes of Health supports research and development of mRNA therapeutics through grants even before the pandemic. Active support from regulatory authorities and government initiatives is driving the market in North America during the forecast period.

mRNA Therapeutics and Vaccine Market Key Players

Examples of the key companies engaged in the mRNA Therapeutics and Vaccine market (which have also been profiled in the market report; the complete list of the companies is also included in the full report) include:

• BioNTec
• Chimeron Bio
• CureVac
• eTheRNA
• IMMORNA
• Moderna
• Omega Therapeutics
• RNACure
• Stemirna Therapeutics.

It is worth noting the ongoing developments and collaborations in the mRNA therapeutics and vaccine market, which anticipate steady growth. An example of such a partnership includes:

• In August, Moderma and CARsgen Therapeutics entered into a collaboration to combine their respective mRNA therapeutics cancer vaccine with a solid tumor CAR-T cell therapy for the treatment of individuals with multiple cancers.
• In June 2023, Providence Therapeutics collaborated with the University Health Network (UHN) to develop mRNA-based therapeutics and vaccines to treat patients with cancer and infectious diseases.
• In April 2023, Moderna and IBM collaborated to explore advanced next generation technologies such as artificial intelligence and quantum computing in order to enhance their mRNA research and science.

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mRNA Therapeutics and Vaccine Market Segments

Based on the research report, Roots Analysis has segmented the mRNA Therapeutics and Vaccine market into the types of secondary packaging, primary packaging, and key geographical regions.

• mRNA Therapeutics and Vaccine Market, Based on Expertise

• mRNA Therapeutics
• mRNA Vaccines

• mRNA Therapeutics and Vaccine Market, Based on Route of Administration

• Intravenous
• Intramuscular
• Intranasal
• Others

• mRNA Therapeutics and Vaccine Market, Based on Key Geographical Regions

• North America
• Europe
• Asia-Pacific
• Middle East and North Africa
• Latin America
• Rest of the World

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