Small Interfering RNA (siRNA) Therapeutics Market Poised for Robust Growth, Projected to Reach USD 39.19 Billion by 2030

Small Interfering RNA (SIRNA) Therapeutics Market is expected to reach US$ 39.19 Bn. at a CAGR of 17.5 % during the forecast period (2024-2030).

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Competitive Landscape and Regional Demand

Key players driving this market include Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Sanofi Genzyme, Silence Therapeutics, GlaxoSmithKline, and Ionis Pharmaceuticals. These companies are at the forefront of developing innovative siRNA-based therapies, contributing to the market's expansion.

North America currently holds the largest market share, attributed to substantial investments in biotechnology and a well-established healthcare infrastructure . However, the Asia Pacific region is anticipated to witness the highest CAGR, driven by increasing healthcare expenditures and a growing prevalence of genetic disorders .

Regional Insights

United States: Growth and Consolidation

The United States remains a dominant force in the siRNA therapeutics market, supported by a robust pharmaceutical infrastructure and significant R&D investments. The FDA's approval of gene therapies has spurred further research and development in this field . Notably, Novartis' acquisition of DTx Pharma in July 2023 underscores the trend of consolidation aimed at enhancing siRNA therapeutic capabilities .

Asia Pacific: Opportunities and Trends

The Asia Pacific region is emerging as a significant growth area for siRNA therapeutics. Countries like China and India are increasing their biotech capabilities, creating a conducive environment for siRNA innovation and commercialization . The rising prevalence of diseases such as cardiovascular conditions and viral infections further drives the demand for siRNA-based treatments .

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Europe: Innovation and Updation

Europe is expected to experience substantial growth in the siRNA therapeutics market, fueled by a strong regulatory environment and increased emphasis on personalized medicine . Companies like Silence Therapeutics, headquartered in London, are pioneering the development of siRNA therapies for rare diseases, contributing to the region's innovative landscape .

Middle East and Africa: Emerging Opportunities

While currently holding a smaller market share, the Middle East and Africa region presents emerging opportunities for siRNA therapeutics. Efforts to improve healthcare infrastructure and increase access to advanced treatments are expected to drive growth in this region .

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Market Segmentation: In-Depth Analysis:

by Type

Liposome Based Systemic Therapy
Nanoparticle Based Systemic Therapy
Other

Based on type, liposome-based systemic therapy is anticipated to have a leading market share since it is the most promising drug delivery technique for in vivo siRNA delivery. The first nano-drug delivery method to be effectively adapted for use in real-time clinical settings is liposomes. The most widely utilized liposome-based delivery systems in clinical settings are expanded by the second and third generations of liposomes' capacity to either boost liposome stabilities or recognize particular receptors. Each of these elements contributes to the growth of the segment.

by Applications

Hospital, Research Institutions
Pharmaceutical and Biotechnology Companies
Academic Institutions
Other

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Learn about the top players driving innovation in the Market :

1. GE Dharmacon
2. OPKO Health, Inc.
3. Alnylam Pharmaceuticals
4. Arrowhead Research Corp
5. Sanofi Genzyme
6. Genecon Biotechnologies Co., Ltd.
7. Arbutus Biopharma Corp
8. Silence Therapeutics AG
9. Sylentis S.A.
10. Olix Pharmaceuticals
11. GlaxoSmithKline
12. Isis Pharmaceuticals/ Ionis Pharmaceuticals
13. BenitecBiopharma Ltd.
14. Bio-Path Holdings Inc.
15. Calando Pharmaceuticals

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